Disease specific cell death gene regulator search
Search Results:
Huntington's Disease (HD) specific necroptosis gene regulaors.
Different color in column1 means high , low , non-diff expressed gene in disease.
NO. | Disease | CellDeathType | Genesymbol | Fullname | Control_mean | Disease_mean | log2FC | pvalue | padj | Weight | Detail |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | Huntington's Disease (HD) | necroptosis | PTPN13 | protein tyrosine phosphatase non-receptor type 13 | 0.5 | -0.24 | -1.06 | 0.0 | 0.58 | 100.0 | Detail |
2 | Huntington's Disease (HD) | necroptosis | TNF | tumor necrosis factor | 0.37 | -0.28 | -0.39 | 0.01 | 0.96 | 80.76 | Detail |
3 | Huntington's Disease (HD) | necroptosis | RNASE3 | ribonuclease A family member 3 | 0.27 | -0.27 | 0.01 | 0.01 | 0.96 | 79.93 | Detail |
4 | Huntington's Disease (HD) | necroptosis | CASP8AP2 | caspase 8 associated protein 2 | -0.41 | 0.17 | -1.29 | 0.01 | 0.96 | 79.28 | Detail |
5 | Huntington's Disease (HD) | necroptosis | MAPK14 | mitogen-activated protein kinase 14 | -0.25 | 0.15 | -0.72 | 0.03 | 0.96 | 70.39 | Detail |
6 | Huntington's Disease (HD) | necroptosis | MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.41 | -0.09 | -2.16 | 0.03 | 0.96 | 70.39 | Detail |
7 | Huntington's Disease (HD) | necroptosis | PFN2 | profilin 2 | -0.32 | 0.2 | -0.72 | 0.04 | 0.96 | 66.45 | Detail |
8 | Huntington's Disease (HD) | necroptosis | IFNAR2 | interferon alpha and beta receptor subunit 2 | -0.42 | 0.15 | -1.48 | 0.05 | 0.96 | 64.47 | Detail |
9 | Huntington's Disease (HD) | necroptosis | CEBPA | CCAAT enhancer binding protein alpha | 0.2 | -0.24 | 0.32 | 0.05 | 0.96 | 62.83 | Detail |
10 | Huntington's Disease (HD) | necroptosis | ARHGDIB | Rho GDP dissociation inhibitor beta | 0.3 | -0.05 | -2.57 | 0.05 | 0.96 | 62.83 | Detail |
11 | Huntington's Disease (HD) | necroptosis | NCS1 | neuronal calcium sensor 1 | 0.47 | -0.07 | -2.74 | 0.06 | 0.96 | 61.84 | Detail |
12 | Huntington's Disease (HD) | necroptosis | MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.22 | 0.13 | -0.81 | 0.06 | 0.96 | 61.51 | Detail |
13 | Huntington's Disease (HD) | necroptosis | MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.29 | 0.15 | -1.0 | 0.06 | 0.96 | 61.51 | Detail |
14 | Huntington's Disease (HD) | necroptosis | RALBP1 | ralA binding protein 1 | 0.38 | -0.11 | -1.77 | 0.06 | 0.96 | 60.53 | Detail |
15 | Huntington's Disease (HD) | necroptosis | TPX2 | TPX2 microtubule nucleation factor | 0.23 | -0.13 | -0.85 | 0.06 | 0.96 | 59.87 | Detail |
16 | Huntington's Disease (HD) | necroptosis | PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | -0.28 | 0.12 | -1.17 | 0.07 | 0.96 | 58.88 | Detail |
17 | Huntington's Disease (HD) | necroptosis | SHARPIN | SHANK associated RH domain interactor | 0.3 | -0.06 | -2.22 | 0.07 | 0.96 | 58.88 | Detail |
18 | Huntington's Disease (HD) | necroptosis | ADAM17 | ADAM metallopeptidase domain 17 | 0.15 | -0.2 | 0.49 | 0.07 | 0.96 | 57.89 | Detail |
19 | Huntington's Disease (HD) | necroptosis | RPS6KA4 | ribosomal protein S6 kinase A4 | 0.24 | -0.17 | -0.52 | 0.07 | 0.96 | 57.89 | Detail |
20 | Huntington's Disease (HD) | necroptosis | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | -0.27 | 0.07 | -1.97 | 0.08 | 0.96 | 57.24 | Detail |
21 | Huntington's Disease (HD) | necroptosis | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | -0.2 | 0.09 | -1.17 | 0.08 | 0.96 | 56.25 | Detail |
22 | Huntington's Disease (HD) | necroptosis | TGFB2 | transforming growth factor beta 2 | 0.25 | -0.1 | -1.26 | 0.09 | 0.96 | 54.93 | Detail |
23 | Huntington's Disease (HD) | necroptosis | GLUD2 | glutamate dehydrogenase 2 | -0.36 | 0.07 | -2.36 | 0.09 | 0.96 | 54.61 | Detail |
24 | Huntington's Disease (HD) | necroptosis | PSEN2 | presenilin 2 | 0.26 | -0.18 | -0.55 | 0.09 | 0.96 | 54.61 | Detail |
25 | Huntington's Disease (HD) | necroptosis | PRKCZ | protein kinase C zeta | -0.1 | 0.12 | 0.17 | 0.1 | 0.96 | 53.62 | Detail |
26 | Huntington's Disease (HD) | necroptosis | EGF | epidermal growth factor | 0.21 | -0.17 | -0.36 | 0.1 | 0.96 | 52.96 | Detail |
27 | Huntington's Disease (HD) | necroptosis | MEF2A | myocyte enhancer factor 2A | -0.32 | 0.02 | -3.74 | 0.1 | 0.96 | 52.96 | Detail |
28 | Huntington's Disease (HD) | necroptosis | CDK2AP1 | cyclin dependent kinase 2 associated protein 1 | 0.16 | -0.19 | 0.2 | 0.1 | 0.96 | 52.63 | Detail |
29 | Huntington's Disease (HD) | necroptosis | CHMP4C | charged multivesicular body protein 4C | -0.15 | 0.31 | 1.04 | 0.11 | 0.96 | 52.3 | Detail |
30 | Huntington's Disease (HD) | necroptosis | JUN | Jun proto-oncogene, AP-1 transcription factor subunit | -0.34 | 0.11 | -1.6 | 0.11 | 0.96 | 51.32 | Detail |
31 | Huntington's Disease (HD) | necroptosis | MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.29 | -0.1 | -1.59 | 0.12 | 0.96 | 50.66 | Detail |
32 | Huntington's Disease (HD) | necroptosis | RFFL | ring finger and FYVE like domain containing E3 ubiquitin protein ligase | -0.28 | 0.05 | -2.57 | 0.13 | 0.96 | 49.67 | Detail |
33 | Huntington's Disease (HD) | necroptosis | SPATA2 | spermatogenesis associated 2 | -0.18 | 0.06 | -1.68 | 0.13 | 0.96 | 49.67 | Detail |
34 | Huntington's Disease (HD) | necroptosis | B4GALNT2 | beta-1,4-N-acetyl-galactosaminyltransferase 2 (SID blood group) | 0.41 | 0.03 | -3.72 | 0.13 | 0.96 | 48.68 | Detail |
35 | Huntington's Disease (HD) | necroptosis | IL1A | interleukin 1 alpha | -0.23 | 0.13 | -0.81 | 0.15 | 0.96 | 47.04 | Detail |
36 | Huntington's Disease (HD) | necroptosis | ZBP1 | Z-DNA binding protein 1 | -0.25 | 0.07 | -1.94 | 0.15 | 0.96 | 46.71 | Detail |
37 | Huntington's Disease (HD) | necroptosis | LMNA | lamin A/C | 0.3 | -0.03 | -3.44 | 0.16 | 0.96 | 45.72 | Detail |
38 | Huntington's Disease (HD) | necroptosis | RNASE1 | ribonuclease A family member 1, pancreatic | -0.22 | 0.17 | -0.41 | 0.16 | 0.96 | 45.39 | Detail |
39 | Huntington's Disease (HD) | necroptosis | IL1B | interleukin 1 beta | -0.18 | 0.11 | -0.73 | 0.17 | 0.96 | 45.07 | Detail |
40 | Huntington's Disease (HD) | necroptosis | PRKCB | protein kinase C beta | -0.24 | -0.03 | -3.03 | 0.17 | 0.96 | 44.08 | Detail |
41 | Huntington's Disease (HD) | necroptosis | DFFB | DNA fragmentation factor subunit beta | -0.22 | 0.02 | -3.7 | 0.18 | 0.96 | 43.75 | Detail |
42 | Huntington's Disease (HD) | necroptosis | DNM1L | dynamin 1 like | -0.37 | 0.09 | -2.06 | 0.18 | 0.96 | 43.75 | Detail |
43 | Huntington's Disease (HD) | necroptosis | HSPB1 | heat shock protein family B (small) member 1 | 0.24 | -0.02 | -3.29 | 0.18 | 0.96 | 43.42 | Detail |
44 | Huntington's Disease (HD) | necroptosis | PRKCA | protein kinase C alpha | 0.3 | -0.01 | -4.63 | 0.18 | 0.96 | 43.42 | Detail |
45 | Huntington's Disease (HD) | necroptosis | CASP9 | caspase 9 | -0.18 | 0.1 | -0.83 | 0.18 | 0.96 | 43.42 | Detail |
46 | Huntington's Disease (HD) | necroptosis | BID | BH3 interacting domain death agonist | 0.15 | -0.18 | 0.25 | 0.19 | 0.96 | 42.43 | Detail |
47 | Huntington's Disease (HD) | necroptosis | RPS6KA3 | ribosomal protein S6 kinase A3 | 0.17 | -0.11 | -0.61 | 0.19 | 0.96 | 42.43 | Detail |
48 | Huntington's Disease (HD) | necroptosis | EPHB2 | EPH receptor B2 | 0.25 | -0.07 | -1.84 | 0.19 | 0.96 | 42.11 | Detail |
49 | Huntington's Disease (HD) | necroptosis | MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.33 | -0.01 | -4.91 | 0.19 | 0.96 | 42.11 | Detail |
50 | Huntington's Disease (HD) | necroptosis | PRKDC | protein kinase, DNA-activated, catalytic subunit | -0.17 | 0.19 | 0.17 | 0.21 | 0.96 | 41.12 | Detail |
51 | Huntington's Disease (HD) | necroptosis | JAK2 | Janus kinase 2 | -0.28 | -0.11 | -1.39 | 0.22 | 0.96 | 40.13 | Detail |
52 | Huntington's Disease (HD) | necroptosis | IKBKG | inhibitor of nuclear factor kappa B kinase regulatory subunit gamma | 0.11 | -0.07 | -0.55 | 0.23 | 0.96 | 38.82 | Detail |
53 | Huntington's Disease (HD) | necroptosis | CLTC | clathrin heavy chain | -0.2 | 0.03 | -2.9 | 0.23 | 0.96 | 38.82 | Detail |
54 | Huntington's Disease (HD) | necroptosis | MEF2D | myocyte enhancer factor 2D | 0.15 | -0.1 | -0.56 | 0.24 | 0.96 | 38.49 | Detail |
55 | Huntington's Disease (HD) | necroptosis | PIK3R2 | phosphoinositide-3-kinase regulatory subunit 2 | 0.37 | -0.11 | -1.8 | 0.24 | 0.96 | 38.49 | Detail |
56 | Huntington's Disease (HD) | necroptosis | CASP2 | caspase 2 | -0.19 | 0.12 | -0.68 | 0.24 | 0.96 | 38.49 | Detail |
57 | Huntington's Disease (HD) | necroptosis | BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.23 | -0.01 | -4.92 | 0.24 | 0.96 | 37.83 | Detail |
58 | Huntington's Disease (HD) | necroptosis | EZR | ezrin | 0.16 | -0.13 | -0.3 | 0.24 | 0.96 | 37.83 | Detail |
59 | Huntington's Disease (HD) | necroptosis | PRKCG | protein kinase C gamma | 0.21 | -0.06 | -1.75 | 0.25 | 0.96 | 37.5 | Detail |
60 | Huntington's Disease (HD) | necroptosis | IFNGR2 | interferon gamma receptor 2 | -0.28 | -0.0 | -6.59 | 0.25 | 0.96 | 37.17 | Detail |
61 | Huntington's Disease (HD) | necroptosis | CASP8 | caspase 8 | 0.23 | -0.05 | -2.36 | 0.26 | 0.96 | 36.51 | Detail |
62 | Huntington's Disease (HD) | necroptosis | MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | -0.21 | 0.01 | -5.11 | 0.26 | 0.96 | 36.51 | Detail |
63 | Huntington's Disease (HD) | necroptosis | PRKCE | protein kinase C epsilon | -0.29 | 0.01 | -4.72 | 0.26 | 0.96 | 36.51 | Detail |
64 | Huntington's Disease (HD) | necroptosis | IFNAR1 | interferon alpha and beta receptor subunit 1 | -0.12 | 0.1 | -0.29 | 0.26 | 0.96 | 36.51 | Detail |
65 | Huntington's Disease (HD) | necroptosis | AGFG1 | ArfGAP with FG repeats 1 | 0.04 | -0.15 | 1.86 | 0.27 | 0.96 | 36.18 | Detail |
66 | Huntington's Disease (HD) | necroptosis | PPIA | peptidylprolyl isomerase A | 0.22 | -0.07 | -1.72 | 0.27 | 0.96 | 36.18 | Detail |
67 | Huntington's Disease (HD) | necroptosis | MAPK13 | mitogen-activated protein kinase 13 | -0.11 | 0.1 | -0.08 | 0.27 | 0.96 | 35.86 | Detail |
68 | Huntington's Disease (HD) | necroptosis | MET | MET proto-oncogene, receptor tyrosine kinase | -0.16 | 0.16 | 0.02 | 0.27 | 0.96 | 35.53 | Detail |
69 | Huntington's Disease (HD) | necroptosis | STAT5B | signal transducer and activator of transcription 5B | -0.04 | 0.09 | 1.12 | 0.27 | 0.96 | 35.53 | Detail |
70 | Huntington's Disease (HD) | necroptosis | DIABLO | diablo IAP-binding mitochondrial protein | -0.18 | 0.07 | -1.43 | 0.29 | 0.96 | 34.54 | Detail |
71 | Huntington's Disease (HD) | necroptosis | JAK1 | Janus kinase 1 | 0.1 | -0.05 | -0.98 | 0.29 | 0.96 | 34.54 | Detail |
72 | Huntington's Disease (HD) | necroptosis | NSMAF | neutral sphingomyelinase activation associated factor | -0.11 | 0.12 | 0.13 | 0.29 | 0.96 | 34.21 | Detail |
73 | Huntington's Disease (HD) | necroptosis | CHMP2A | charged multivesicular body protein 2A | -0.1 | 0.09 | -0.21 | 0.3 | 0.96 | 33.88 | Detail |
74 | Huntington's Disease (HD) | necroptosis | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | -0.12 | 0.05 | -1.32 | 0.3 | 0.96 | 33.55 | Detail |
75 | Huntington's Disease (HD) | necroptosis | CSNK1A1 | casein kinase 1 alpha 1 | -0.2 | -0.05 | -2.14 | 0.3 | 0.96 | 33.55 | Detail |
76 | Huntington's Disease (HD) | necroptosis | STAT2 | signal transducer and activator of transcription 2 | -0.11 | 0.06 | -0.85 | 0.3 | 0.96 | 33.55 | Detail |
77 | Huntington's Disease (HD) | necroptosis | MLKL | mixed lineage kinase domain like pseudokinase | -0.09 | 0.07 | -0.39 | 0.31 | 0.96 | 33.22 | Detail |
78 | Huntington's Disease (HD) | necroptosis | MAPKAPK2 | MAPK activated protein kinase 2 | 0.13 | -0.11 | -0.23 | 0.32 | 0.96 | 32.57 | Detail |
79 | Huntington's Disease (HD) | necroptosis | PYCARD | PYD and CARD domain containing | -0.13 | 0.0 | -5.12 | 0.32 | 0.96 | 32.57 | Detail |
80 | Huntington's Disease (HD) | necroptosis | MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | -0.18 | 0.05 | -1.97 | 0.32 | 0.96 | 32.24 | Detail |
81 | Huntington's Disease (HD) | necroptosis | MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | -0.1 | 0.08 | -0.26 | 0.32 | 0.96 | 32.24 | Detail |
82 | Huntington's Disease (HD) | necroptosis | MKNK2 | MAPK interacting serine/threonine kinase 2 | 0.24 | -0.03 | -3.13 | 0.32 | 0.96 | 32.24 | Detail |
83 | Huntington's Disease (HD) | necroptosis | MAPKAPK3 | MAPK activated protein kinase 3 | 0.13 | -0.06 | -1.06 | 0.33 | 0.96 | 31.91 | Detail |
84 | Huntington's Disease (HD) | necroptosis | MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.21 | 0.06 | -1.82 | 0.33 | 0.96 | 31.58 | Detail |
85 | Huntington's Disease (HD) | necroptosis | TGFB1 | transforming growth factor beta 1 | 0.11 | -0.06 | -0.97 | 0.34 | 0.96 | 31.25 | Detail |
86 | Huntington's Disease (HD) | necroptosis | SLC19A1 | solute carrier family 19 member 1 | 0.24 | 0.04 | -2.74 | 0.34 | 0.96 | 31.25 | Detail |
87 | Huntington's Disease (HD) | necroptosis | HOXA7 | homeobox A7 | 0.11 | 0.03 | -1.74 | 0.34 | 0.96 | 31.25 | Detail |
88 | Huntington's Disease (HD) | necroptosis | PSEN1 | presenilin 1 | -0.28 | -0.02 | -3.5 | 0.34 | 0.96 | 30.92 | Detail |
89 | Huntington's Disease (HD) | necroptosis | CFLAR | CASP8 and FADD like apoptosis regulator | -0.06 | 0.04 | -0.69 | 0.35 | 0.96 | 30.26 | Detail |
90 | Huntington's Disease (HD) | necroptosis | MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.13 | -0.07 | -0.84 | 0.35 | 0.96 | 30.26 | Detail |
91 | Huntington's Disease (HD) | necroptosis | MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.19 | -0.04 | -2.17 | 0.36 | 0.96 | 29.93 | Detail |
92 | Huntington's Disease (HD) | necroptosis | MAPK11 | mitogen-activated protein kinase 11 | -0.02 | 0.17 | 3.17 | 0.36 | 0.96 | 29.61 | Detail |
93 | Huntington's Disease (HD) | necroptosis | LMNB2 | lamin B2 | 0.09 | -0.03 | -1.77 | 0.37 | 0.96 | 29.44 | Detail |
94 | Huntington's Disease (HD) | necroptosis | AKT1 | AKT serine/threonine kinase 1 | 0.13 | -0.1 | -0.41 | 0.37 | 0.96 | 29.28 | Detail |
95 | Huntington's Disease (HD) | necroptosis | SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.22 | 0.03 | -2.8 | 0.37 | 0.96 | 29.28 | Detail |
96 | Huntington's Disease (HD) | necroptosis | STAT1 | signal transducer and activator of transcription 1 | -0.14 | 0.05 | -1.61 | 0.38 | 0.96 | 28.62 | Detail |
97 | Huntington's Disease (HD) | necroptosis | MAX | MYC associated factor X | 0.14 | -0.12 | -0.15 | 0.38 | 0.96 | 28.29 | Detail |
98 | Huntington's Disease (HD) | necroptosis | RPS6KB1 | ribosomal protein S6 kinase B1 | -0.08 | 0.0 | -4.92 | 0.38 | 0.96 | 28.29 | Detail |
99 | Huntington's Disease (HD) | necroptosis | MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.1 | -0.19 | 0.96 | 0.38 | 0.96 | 28.29 | Detail |
100 | Huntington's Disease (HD) | necroptosis | AIFM1 | apoptosis inducing factor mitochondria associated 1 | -0.01 | -0.07 | 3.47 | 0.38 | 0.96 | 28.29 | Detail |
101 | Huntington's Disease (HD) | necroptosis | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1 | -0.11 | 0.05 | -1.02 | 0.38 | 0.96 | 28.29 | Detail |
102 | Huntington's Disease (HD) | necroptosis | SMPD1 | sphingomyelin phosphodiesterase 1 | -0.08 | 0.06 | -0.59 | 0.39 | 0.96 | 27.96 | Detail |
103 | Huntington's Disease (HD) | necroptosis | PTK2 | protein tyrosine kinase 2 | -0.25 | 0.12 | -1.0 | 0.39 | 0.96 | 27.96 | Detail |
104 | Huntington's Disease (HD) | necroptosis | RPS6KA5 | ribosomal protein S6 kinase A5 | -0.07 | 0.02 | -1.49 | 0.39 | 0.96 | 27.96 | Detail |
105 | Huntington's Disease (HD) | necroptosis | CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.12 | 0.02 | -2.53 | 0.39 | 0.96 | 27.96 | Detail |
106 | Huntington's Disease (HD) | necroptosis | EGFR | epidermal growth factor receptor | 0.13 | -0.04 | -1.82 | 0.4 | 0.96 | 27.63 | Detail |
107 | Huntington's Disease (HD) | necroptosis | MAPK4 | mitogen-activated protein kinase 4 | 0.17 | 0.01 | -3.64 | 0.4 | 0.96 | 27.63 | Detail |
108 | Huntington's Disease (HD) | necroptosis | FTH1 | ferritin heavy chain 1 | -0.13 | 0.08 | -0.57 | 0.4 | 0.96 | 27.63 | Detail |
109 | Huntington's Disease (HD) | necroptosis | CAPN2 | calpain 2 | -0.03 | 0.09 | 1.69 | 0.4 | 0.96 | 27.63 | Detail |
110 | Huntington's Disease (HD) | necroptosis | FASLG | Fas ligand | 0.19 | -0.08 | -1.26 | 0.4 | 0.96 | 27.3 | Detail |
111 | Huntington's Disease (HD) | necroptosis | TNIK | TRAF2 and NCK interacting kinase | -0.1 | 0.07 | -0.44 | 0.4 | 0.96 | 27.3 | Detail |
112 | Huntington's Disease (HD) | necroptosis | TLR3 | toll like receptor 3 | -0.1 | -0.01 | -3.19 | 0.4 | 0.96 | 27.3 | Detail |
113 | Huntington's Disease (HD) | necroptosis | FTL | ferritin light chain | 0.11 | -0.1 | -0.14 | 0.4 | 0.96 | 27.3 | Detail |
114 | Huntington's Disease (HD) | necroptosis | TP53 | tumor protein p53 | -0.09 | 0.09 | 0.13 | 0.41 | 0.96 | 26.97 | Detail |
115 | Huntington's Disease (HD) | necroptosis | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.06 | -0.08 | 0.37 | 0.41 | 0.96 | 26.97 | Detail |
116 | Huntington's Disease (HD) | necroptosis | DEDD2 | death effector domain containing 2 | 0.11 | -0.06 | -0.77 | 0.41 | 0.96 | 26.97 | Detail |
117 | Huntington's Disease (HD) | necroptosis | CXCL8 | C-X-C motif chemokine ligand 8 | -0.06 | 0.06 | -0.08 | 0.41 | 0.96 | 26.64 | Detail |
118 | Huntington's Disease (HD) | necroptosis | PRKCQ | protein kinase C theta | -0.02 | 0.09 | 2.06 | 0.41 | 0.96 | 26.64 | Detail |
119 | Huntington's Disease (HD) | necroptosis | PRKCI | protein kinase C iota | -0.18 | -0.06 | -1.61 | 0.41 | 0.96 | 26.64 | Detail |
120 | Huntington's Disease (HD) | necroptosis | PARP1 | poly(ADP-ribose) polymerase 1 | 0.14 | -0.0 | -6.23 | 0.42 | 0.96 | 26.48 | Detail |
121 | Huntington's Disease (HD) | necroptosis | TNFRSF10B | TNF receptor superfamily member 10b | 0.09 | -0.12 | 0.47 | 0.42 | 0.96 | 26.32 | Detail |
122 | Huntington's Disease (HD) | necroptosis | IRF9 | interferon regulatory factor 9 | -0.12 | 0.07 | -0.7 | 0.42 | 0.96 | 26.32 | Detail |
123 | Huntington's Disease (HD) | necroptosis | PIK3R3 | phosphoinositide-3-kinase regulatory subunit 3 | -0.01 | -0.11 | 4.33 | 0.43 | 0.96 | 25.66 | Detail |
124 | Huntington's Disease (HD) | necroptosis | MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.0 | 0.03 | 3.06 | 0.43 | 0.96 | 25.66 | Detail |
125 | Huntington's Disease (HD) | necroptosis | ETS2 | ETS proto-oncogene 2, transcription factor | -0.17 | 0.04 | -2.22 | 0.44 | 0.96 | 25.33 | Detail |
126 | Huntington's Disease (HD) | necroptosis | MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | -0.12 | 0.05 | -1.13 | 0.44 | 0.96 | 25.33 | Detail |
127 | Huntington's Disease (HD) | necroptosis | FAS | Fas cell surface death receptor | -0.01 | -0.04 | 2.02 | 0.44 | 0.96 | 25.0 | Detail |
128 | Huntington's Disease (HD) | necroptosis | CYLD | CYLD lysine 63 deubiquitinase | -0.14 | 0.01 | -4.03 | 0.44 | 0.96 | 25.0 | Detail |
129 | Huntington's Disease (HD) | necroptosis | MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | -0.2 | 0.05 | -1.93 | 0.44 | 0.96 | 25.0 | Detail |
130 | Huntington's Disease (HD) | necroptosis | CREB1 | cAMP responsive element binding protein 1 | 0.08 | -0.16 | 1.03 | 0.45 | 0.96 | 24.67 | Detail |
131 | Huntington's Disease (HD) | necroptosis | RELA | RELA proto-oncogene, NF-kB subunit | 0.08 | -0.02 | -2.18 | 0.45 | 0.96 | 24.67 | Detail |
132 | Huntington's Disease (HD) | necroptosis | ARAF | A-Raf proto-oncogene, serine/threonine kinase | 0.16 | -0.12 | -0.4 | 0.45 | 0.96 | 24.34 | Detail |
133 | Huntington's Disease (HD) | necroptosis | RFC1 | replication factor C subunit 1 | -0.09 | 0.08 | -0.25 | 0.45 | 0.96 | 24.34 | Detail |
134 | Huntington's Disease (HD) | necroptosis | CHMP2B | charged multivesicular body protein 2B | -0.21 | -0.05 | -2.03 | 0.47 | 0.96 | 23.68 | Detail |
135 | Huntington's Disease (HD) | necroptosis | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 | 0.22 | -0.0 | -6.28 | 0.47 | 0.96 | 23.68 | Detail |
136 | Huntington's Disease (HD) | necroptosis | SYK | spleen associated tyrosine kinase | -0.11 | 0.04 | -1.56 | 0.47 | 0.96 | 23.36 | Detail |
137 | Huntington's Disease (HD) | necroptosis | RPS6KB2 | ribosomal protein S6 kinase B2 | 0.21 | -0.02 | -3.84 | 0.47 | 0.96 | 23.36 | Detail |
138 | Huntington's Disease (HD) | necroptosis | TNFRSF10A | TNF receptor superfamily member 10a | -0.06 | 0.06 | 0.13 | 0.47 | 0.96 | 23.36 | Detail |
139 | Huntington's Disease (HD) | necroptosis | MEF2C | myocyte enhancer factor 2C | -0.25 | -0.04 | -2.77 | 0.47 | 0.96 | 23.36 | Detail |
140 | Huntington's Disease (HD) | necroptosis | RB1 | RB transcriptional corepressor 1 | -0.16 | -0.03 | -2.47 | 0.48 | 0.96 | 23.03 | Detail |
141 | Huntington's Disease (HD) | necroptosis | RIPK1 | receptor interacting serine/threonine kinase 1 | 0.14 | -0.05 | -1.49 | 0.49 | 0.96 | 22.7 | Detail |
142 | Huntington's Disease (HD) | necroptosis | MAPK7 | mitogen-activated protein kinase 7 | 0.11 | -0.04 | -1.35 | 0.49 | 0.96 | 22.7 | Detail |
143 | Huntington's Disease (HD) | necroptosis | CASP1 | caspase 1 | -0.19 | -0.03 | -2.69 | 0.49 | 0.96 | 22.7 | Detail |
144 | Huntington's Disease (HD) | necroptosis | BAK1 | BCL2 antagonist/killer 1 | 0.15 | -0.02 | -3.02 | 0.5 | 0.96 | 22.04 | Detail |
145 | Huntington's Disease (HD) | necroptosis | RAC1 | Rac family small GTPase 1 | 0.12 | -0.13 | 0.13 | 0.5 | 0.96 | 22.04 | Detail |
146 | Huntington's Disease (HD) | necroptosis | MAPK10 | mitogen-activated protein kinase 10 | 0.24 | -0.01 | -4.76 | 0.5 | 0.96 | 22.04 | Detail |
147 | Huntington's Disease (HD) | necroptosis | FASN | fatty acid synthase | 0.23 | 0.04 | -2.38 | 0.51 | 0.96 | 21.71 | Detail |
148 | Huntington's Disease (HD) | necroptosis | MADD | MAP kinase activating death domain | 0.12 | -0.04 | -1.74 | 0.51 | 0.96 | 21.71 | Detail |
149 | Huntington's Disease (HD) | necroptosis | MAPK12 | mitogen-activated protein kinase 12 | 0.19 | 0.02 | -2.98 | 0.51 | 0.96 | 21.71 | Detail |
150 | Huntington's Disease (HD) | necroptosis | TXN | thioredoxin | -0.16 | 0.07 | -1.19 | 0.51 | 0.96 | 21.38 | Detail |
151 | Huntington's Disease (HD) | necroptosis | PGAM5 | PGAM family member 5, mitochondrial serine/threonine protein phosphatase | 0.12 | 0.01 | -3.24 | 0.51 | 0.96 | 21.38 | Detail |
152 | Huntington's Disease (HD) | necroptosis | PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | -0.03 | -0.15 | 2.18 | 0.52 | 0.96 | 21.05 | Detail |
153 | Huntington's Disease (HD) | necroptosis | SLTM | SAFB like transcription modulator | -0.05 | -0.06 | 0.04 | 0.52 | 0.96 | 21.05 | Detail |
154 | Huntington's Disease (HD) | necroptosis | RPS6KA2 | ribosomal protein S6 kinase A2 | 0.01 | -0.04 | 2.69 | 0.52 | 0.96 | 21.05 | Detail |
155 | Huntington's Disease (HD) | necroptosis | ETFA | electron transfer flavoprotein subunit alpha | 0.02 | -0.21 | 3.78 | 0.52 | 0.96 | 21.05 | Detail |
156 | Huntington's Disease (HD) | necroptosis | MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | -0.03 | 0.09 | 1.79 | 0.52 | 0.96 | 20.72 | Detail |
157 | Huntington's Disease (HD) | necroptosis | CD7 | CD7 molecule | 0.04 | 0.15 | 1.79 | 0.52 | 0.96 | 20.72 | Detail |
158 | Huntington's Disease (HD) | necroptosis | IFNGR1 | interferon gamma receptor 1 | -0.2 | 0.01 | -4.66 | 0.53 | 0.96 | 20.39 | Detail |
159 | Huntington's Disease (HD) | necroptosis | CHMP7 | charged multivesicular body protein 7 | -0.08 | 0.09 | 0.16 | 0.53 | 0.96 | 20.39 | Detail |
160 | Huntington's Disease (HD) | necroptosis | MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.19 | -0.02 | -3.17 | 0.55 | 0.96 | 19.74 | Detail |
161 | Huntington's Disease (HD) | necroptosis | MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | 0.16 | 0.06 | -1.44 | 0.55 | 0.96 | 19.41 | Detail |
162 | Huntington's Disease (HD) | necroptosis | MAPKAPK5 | MAPK activated protein kinase 5 | -0.11 | 0.04 | -1.26 | 0.55 | 0.96 | 19.41 | Detail |
163 | Huntington's Disease (HD) | necroptosis | GAS2 | growth arrest specific 2 | -0.17 | 0.05 | -1.76 | 0.57 | 0.96 | 18.75 | Detail |
164 | Huntington's Disease (HD) | necroptosis | JAK3 | Janus kinase 3 | -0.03 | 0.08 | 1.4 | 0.57 | 0.96 | 18.75 | Detail |
165 | Huntington's Disease (HD) | necroptosis | NFKBIA | NFKB inhibitor alpha | 0.16 | 0.03 | -2.4 | 0.57 | 0.96 | 18.42 | Detail |
166 | Huntington's Disease (HD) | necroptosis | MKNK1 | MAPK interacting serine/threonine kinase 1 | -0.04 | 0.03 | -0.31 | 0.57 | 0.96 | 18.42 | Detail |
167 | Huntington's Disease (HD) | necroptosis | SQSTM1 | sequestosome 1 | -0.06 | 0.04 | -0.72 | 0.57 | 0.96 | 18.42 | Detail |
168 | Huntington's Disease (HD) | necroptosis | PPID | peptidylprolyl isomerase D | -0.09 | 0.0 | -5.52 | 0.57 | 0.96 | 18.42 | Detail |
169 | Huntington's Disease (HD) | necroptosis | BTK | Bruton tyrosine kinase | -0.19 | -0.13 | -0.57 | 0.59 | 0.96 | 17.43 | Detail |
170 | Huntington's Disease (HD) | necroptosis | NFKBIB | NFKB inhibitor beta | -0.07 | 0.06 | -0.43 | 0.59 | 0.96 | 17.43 | Detail |
171 | Huntington's Disease (HD) | necroptosis | SMPD2 | sphingomyelin phosphodiesterase 2 | 0.13 | -0.06 | -1.21 | 0.59 | 0.96 | 17.43 | Detail |
172 | Huntington's Disease (HD) | necroptosis | CAV1 | caveolin 1 | 0.17 | 0.01 | -3.71 | 0.6 | 0.96 | 17.11 | Detail |
173 | Huntington's Disease (HD) | necroptosis | MAPK3 | mitogen-activated protein kinase 3 | -0.04 | 0.03 | -0.37 | 0.61 | 0.96 | 16.78 | Detail |
174 | Huntington's Disease (HD) | necroptosis | CASP10 | caspase 10 | -0.06 | 0.07 | 0.12 | 0.61 | 0.96 | 16.78 | Detail |
175 | Huntington's Disease (HD) | necroptosis | TUFM | Tu translation elongation factor, mitochondrial | 0.09 | 0.09 | 0.13 | 0.61 | 0.96 | 16.78 | Detail |
176 | Huntington's Disease (HD) | necroptosis | BCL2 | BCL2 apoptosis regulator | -0.04 | 0.03 | -0.21 | 0.62 | 0.96 | 16.12 | Detail |
177 | Huntington's Disease (HD) | necroptosis | FAIM2 | Fas apoptotic inhibitory molecule 2 | 0.11 | 0.03 | -2.11 | 0.62 | 0.96 | 16.12 | Detail |
178 | Huntington's Disease (HD) | necroptosis | CREBBP | CREB binding protein | -0.04 | 0.02 | -0.61 | 0.62 | 0.96 | 16.12 | Detail |
179 | Huntington's Disease (HD) | necroptosis | CHUK | component of inhibitor of nuclear factor kappa B kinase complex | 0.06 | -0.08 | 0.43 | 0.63 | 0.96 | 15.79 | Detail |
180 | Huntington's Disease (HD) | necroptosis | CYCS | cytochrome c, somatic | 0.11 | 0.02 | -2.69 | 0.63 | 0.96 | 15.79 | Detail |
181 | Huntington's Disease (HD) | necroptosis | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2 | -0.01 | -0.04 | 1.62 | 0.63 | 0.96 | 15.79 | Detail |
182 | Huntington's Disease (HD) | necroptosis | TANK | TRAF family member associated NFKB activator | 0.0 | -0.07 | 4.3 | 0.63 | 0.96 | 15.79 | Detail |
183 | Huntington's Disease (HD) | necroptosis | CAPN1 | calpain 1 | 0.15 | -0.01 | -3.71 | 0.63 | 0.96 | 15.79 | Detail |
184 | Huntington's Disease (HD) | necroptosis | SHC1 | SHC adaptor protein 1 | 0.14 | 0.04 | -1.99 | 0.64 | 0.96 | 15.46 | Detail |
185 | Huntington's Disease (HD) | necroptosis | DAXX | death domain associated protein | 0.09 | 0.0 | -4.84 | 0.64 | 0.96 | 15.46 | Detail |
186 | Huntington's Disease (HD) | necroptosis | CASP6 | caspase 6 | -0.07 | 0.14 | 1.04 | 0.65 | 0.96 | 14.8 | Detail |
187 | Huntington's Disease (HD) | necroptosis | BIRC3 | baculoviral IAP repeat containing 3 | -0.05 | 0.0 | -3.47 | 0.65 | 0.96 | 14.8 | Detail |
188 | Huntington's Disease (HD) | necroptosis | FAF1 | Fas associated factor 1 | -0.09 | -0.02 | -2.49 | 0.66 | 0.96 | 14.47 | Detail |
189 | Huntington's Disease (HD) | necroptosis | MAPK1 | mitogen-activated protein kinase 1 | 0.07 | -0.08 | 0.24 | 0.66 | 0.96 | 14.47 | Detail |
190 | Huntington's Disease (HD) | necroptosis | PAK1 | p21 (RAC1) activated kinase 1 | -0.03 | -0.01 | -2.0 | 0.67 | 0.96 | 14.14 | Detail |
191 | Huntington's Disease (HD) | necroptosis | APAF1 | apoptotic peptidase activating factor 1 | -0.08 | -0.06 | -0.3 | 0.67 | 0.96 | 14.14 | Detail |
192 | Huntington's Disease (HD) | necroptosis | PPP2CA | protein phosphatase 2 catalytic subunit alpha | -0.12 | -0.05 | -1.19 | 0.67 | 0.96 | 14.14 | Detail |
193 | Huntington's Disease (HD) | necroptosis | IL33 | interleukin 33 | 0.24 | 0.02 | -3.31 | 0.67 | 0.96 | 14.14 | Detail |
194 | Huntington's Disease (HD) | necroptosis | GSN | gelsolin | 0.03 | -0.11 | 1.69 | 0.68 | 0.96 | 13.49 | Detail |
195 | Huntington's Disease (HD) | necroptosis | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | -0.02 | -0.06 | 1.82 | 0.68 | 0.96 | 13.49 | Detail |
196 | Huntington's Disease (HD) | necroptosis | MAPK8 | mitogen-activated protein kinase 8 | -0.14 | -0.05 | -1.49 | 0.69 | 0.96 | 13.16 | Detail |
197 | Huntington's Disease (HD) | necroptosis | CHMP4B | charged multivesicular body protein 4B | -0.05 | -0.04 | -0.45 | 0.69 | 0.96 | 13.16 | Detail |
198 | Huntington's Disease (HD) | necroptosis | ELK1 | ETS transcription factor ELK1 | 0.11 | 0.03 | -1.69 | 0.7 | 0.96 | 12.83 | Detail |
199 | Huntington's Disease (HD) | necroptosis | SPTAN1 | spectrin alpha, non-erythrocytic 1 | 0.09 | 0.12 | 0.33 | 0.7 | 0.96 | 12.83 | Detail |
200 | Huntington's Disease (HD) | necroptosis | ETS1 | ETS proto-oncogene 1, transcription factor | 0.07 | 0.11 | 0.7 | 0.7 | 0.96 | 12.5 | Detail |
201 | Huntington's Disease (HD) | necroptosis | PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.08 | 0.01 | -2.74 | 0.7 | 0.96 | 12.5 | Detail |
202 | Huntington's Disease (HD) | necroptosis | MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | -0.02 | 0.05 | 1.04 | 0.7 | 0.96 | 12.5 | Detail |
203 | Huntington's Disease (HD) | necroptosis | VDAC1 | voltage dependent anion channel 1 | -0.03 | -0.0 | -2.83 | 0.7 | 0.96 | 12.5 | Detail |
204 | Huntington's Disease (HD) | necroptosis | IKBKB | inhibitor of nuclear factor kappa B kinase subunit beta | -0.05 | 0.07 | 0.57 | 0.71 | 0.96 | 12.17 | Detail |
205 | Huntington's Disease (HD) | necroptosis | TRAF6 | TNF receptor associated factor 6 | -0.14 | -0.0 | -5.25 | 0.71 | 0.96 | 12.17 | Detail |
206 | Huntington's Disease (HD) | necroptosis | TRAF1 | TNF receptor associated factor 1 | -0.12 | 0.08 | -0.63 | 0.71 | 0.96 | 12.17 | Detail |
207 | Huntington's Disease (HD) | necroptosis | MDM2 | MDM2 proto-oncogene | -0.15 | -0.02 | -2.94 | 0.72 | 0.96 | 11.84 | Detail |
208 | Huntington's Disease (HD) | necroptosis | ALOX15 | arachidonate 15-lipoxygenase | -0.09 | -0.0 | -4.17 | 0.72 | 0.96 | 11.84 | Detail |
209 | Huntington's Disease (HD) | necroptosis | STAT3 | signal transducer and activator of transcription 3 | -0.02 | -0.0 | -2.14 | 0.72 | 0.96 | 11.84 | Detail |
210 | Huntington's Disease (HD) | necroptosis | STAT5A | signal transducer and activator of transcription 5A | 0.03 | 0.01 | -1.06 | 0.73 | 0.96 | 11.18 | Detail |
211 | Huntington's Disease (HD) | necroptosis | EP300 | E1A binding protein p300 | -0.15 | 0.09 | -0.73 | 0.74 | 0.96 | 10.86 | Detail |
212 | Huntington's Disease (HD) | necroptosis | STAT4 | signal transducer and activator of transcription 4 | -0.03 | 0.08 | 1.55 | 0.74 | 0.96 | 10.86 | Detail |
213 | Huntington's Disease (HD) | necroptosis | MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.08 | -0.04 | -0.99 | 0.75 | 0.96 | 10.53 | Detail |
214 | Huntington's Disease (HD) | necroptosis | RNF31 | ring finger protein 31 | 0.01 | 0.05 | 2.66 | 0.75 | 0.96 | 10.53 | Detail |
215 | Huntington's Disease (HD) | necroptosis | DFFA | DNA fragmentation factor subunit alpha | 0.03 | -0.03 | -0.18 | 0.76 | 0.96 | 10.2 | Detail |
216 | Huntington's Disease (HD) | necroptosis | MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.14 | -0.02 | -2.72 | 0.76 | 0.96 | 10.2 | Detail |
217 | Huntington's Disease (HD) | necroptosis | MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.05 | -0.02 | -1.47 | 0.76 | 0.96 | 10.2 | Detail |
218 | Huntington's Disease (HD) | necroptosis | PAK2 | p21 (RAC1) activated kinase 2 | -0.11 | -0.06 | -0.88 | 0.76 | 0.96 | 10.2 | Detail |
219 | Huntington's Disease (HD) | necroptosis | TNFRSF25 | TNF receptor superfamily member 25 | 0.14 | 0.05 | -1.44 | 0.76 | 0.96 | 9.87 | Detail |
220 | Huntington's Disease (HD) | necroptosis | HDAC3 | histone deacetylase 3 | 0.04 | -0.01 | -2.19 | 0.76 | 0.96 | 9.87 | Detail |
221 | Huntington's Disease (HD) | necroptosis | NUMA1 | nuclear mitotic apparatus protein 1 | -0.06 | 0.1 | 0.79 | 0.76 | 0.96 | 9.87 | Detail |
222 | Huntington's Disease (HD) | necroptosis | KCNH4 | potassium voltage-gated channel subfamily H member 4 | 0.05 | 0.09 | 0.8 | 0.76 | 0.96 | 9.87 | Detail |
223 | Huntington's Disease (HD) | necroptosis | TONSL | tonsoku like, DNA repair protein | 0.07 | 0.07 | 0.05 | 0.76 | 0.96 | 9.87 | Detail |
224 | Huntington's Disease (HD) | necroptosis | CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.1 | 0.09 | -0.08 | 0.77 | 0.96 | 9.54 | Detail |
225 | Huntington's Disease (HD) | necroptosis | TNFSF10 | TNF superfamily member 10 | 0.02 | -0.02 | -0.31 | 0.77 | 0.96 | 9.54 | Detail |
226 | Huntington's Disease (HD) | necroptosis | BAG4 | BAG cochaperone 4 | -0.06 | -0.03 | -0.74 | 0.77 | 0.96 | 9.54 | Detail |
227 | Huntington's Disease (HD) | necroptosis | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | -0.05 | 0.0 | -4.22 | 0.77 | 0.96 | 9.54 | Detail |
228 | Huntington's Disease (HD) | necroptosis | USP21 | ubiquitin specific peptidase 21 | -0.0 | 0.05 | 5.54 | 0.78 | 0.96 | 9.21 | Detail |
229 | Huntington's Disease (HD) | necroptosis | NFKB2 | nuclear factor kappa B subunit 2 | -0.02 | -0.04 | 1.09 | 0.79 | 0.96 | 8.88 | Detail |
230 | Huntington's Disease (HD) | necroptosis | MYC | MYC proto-oncogene, bHLH transcription factor | -0.08 | 0.02 | -1.94 | 0.79 | 0.96 | 8.88 | Detail |
231 | Huntington's Disease (HD) | necroptosis | PIK3R1 | phosphoinositide-3-kinase regulatory subunit 1 | -0.01 | 0.08 | 3.8 | 0.79 | 0.96 | 8.88 | Detail |
232 | Huntington's Disease (HD) | necroptosis | XIAP | X-linked inhibitor of apoptosis | -0.02 | -0.05 | 1.57 | 0.79 | 0.96 | 8.88 | Detail |
233 | Huntington's Disease (HD) | necroptosis | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1 | 0.1 | -0.03 | -1.62 | 0.8 | 0.96 | 8.55 | Detail |
234 | Huntington's Disease (HD) | necroptosis | DEDD | death effector domain containing | -0.03 | -0.04 | 0.54 | 0.8 | 0.96 | 8.55 | Detail |
235 | Huntington's Disease (HD) | necroptosis | BIRC2 | baculoviral IAP repeat containing 2 | 0.01 | -0.03 | 1.8 | 0.8 | 0.96 | 8.55 | Detail |
236 | Huntington's Disease (HD) | necroptosis | TRAF5 | TNF receptor associated factor 5 | -0.06 | 0.05 | -0.21 | 0.8 | 0.96 | 8.55 | Detail |
237 | Huntington's Disease (HD) | necroptosis | CHMP5 | charged multivesicular body protein 5 | 0.02 | -0.04 | 1.19 | 0.8 | 0.96 | 8.55 | Detail |
238 | Huntington's Disease (HD) | necroptosis | TGFB3 | transforming growth factor beta 3 | -0.0 | 0.02 | 2.71 | 0.8 | 0.96 | 8.22 | Detail |
239 | Huntington's Disease (HD) | necroptosis | MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.11 | -0.0 | -4.61 | 0.8 | 0.96 | 8.22 | Detail |
240 | Huntington's Disease (HD) | necroptosis | TLR4 | toll like receptor 4 | -0.01 | -0.06 | 2.82 | 0.81 | 0.97 | 7.89 | Detail |
241 | Huntington's Disease (HD) | necroptosis | MAPK9 | mitogen-activated protein kinase 9 | -0.11 | -0.06 | -0.87 | 0.82 | 0.98 | 7.57 | Detail |
242 | Huntington's Disease (HD) | necroptosis | TGFBR1 | transforming growth factor beta receptor 1 | -0.09 | -0.11 | 0.34 | 0.83 | 0.98 | 7.24 | Detail |
243 | Huntington's Disease (HD) | necroptosis | SP1 | Sp1 transcription factor | -0.09 | -0.0 | -5.28 | 0.83 | 0.98 | 6.91 | Detail |
244 | Huntington's Disease (HD) | necroptosis | HRAS | HRas proto-oncogene, GTPase | 0.1 | 0.03 | -1.67 | 0.83 | 0.98 | 6.91 | Detail |
245 | Huntington's Disease (HD) | necroptosis | GLUD1 | glutamate dehydrogenase 1 | -0.07 | -0.05 | -0.43 | 0.84 | 0.99 | 6.58 | Detail |
246 | Huntington's Disease (HD) | necroptosis | PRKCD | protein kinase C delta | -0.05 | -0.02 | -1.24 | 0.86 | 1.0 | 5.92 | Detail |
247 | Huntington's Disease (HD) | necroptosis | RIPK3 | receptor interacting serine/threonine kinase 3 | -0.04 | 0.03 | -0.69 | 0.86 | 1.0 | 5.92 | Detail |
248 | Huntington's Disease (HD) | necroptosis | PKN1 | protein kinase N1 | -0.0 | 0.01 | 2.88 | 0.87 | 1.0 | 5.59 | Detail |
249 | Huntington's Disease (HD) | necroptosis | MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.12 | -0.04 | -1.43 | 0.87 | 1.0 | 5.26 | Detail |
250 | Huntington's Disease (HD) | necroptosis | RPS6KA1 | ribosomal protein S6 kinase A1 | 0.05 | 0.01 | -1.9 | 0.87 | 1.0 | 5.26 | Detail |
251 | Huntington's Disease (HD) | necroptosis | GDNF | glial cell derived neurotrophic factor | 0.03 | 0.05 | 0.73 | 0.88 | 1.0 | 4.93 | Detail |
252 | Huntington's Disease (HD) | necroptosis | TYK2 | tyrosine kinase 2 | 0.02 | -0.02 | -0.16 | 0.89 | 1.0 | 4.61 | Detail |
253 | Huntington's Disease (HD) | necroptosis | CASP3 | caspase 3 | -0.0 | -0.06 | 4.18 | 0.9 | 1.0 | 4.28 | Detail |
254 | Huntington's Disease (HD) | necroptosis | FADD | Fas associated via death domain | 0.04 | 0.03 | -0.46 | 0.9 | 1.0 | 4.28 | Detail |
255 | Huntington's Disease (HD) | necroptosis | TRAF2 | TNF receptor associated factor 2 | 0.12 | 0.04 | -1.37 | 0.9 | 1.0 | 4.28 | Detail |
256 | Huntington's Disease (HD) | necroptosis | HMGB1 | high mobility group box 1 | 0.06 | -0.04 | -0.58 | 0.91 | 1.0 | 3.95 | Detail |
257 | Huntington's Disease (HD) | necroptosis | CHMP6 | charged multivesicular body protein 6 | 0.0 | 0.05 | 3.6 | 0.91 | 1.0 | 3.62 | Detail |
258 | Huntington's Disease (HD) | necroptosis | TRADD | TNFRSF1A associated via death domain | 0.06 | 0.02 | -1.68 | 0.92 | 1.0 | 3.29 | Detail |
259 | Huntington's Disease (HD) | necroptosis | VDAC2 | voltage dependent anion channel 2 | -0.01 | 0.03 | 1.04 | 0.92 | 1.0 | 3.29 | Detail |
260 | Huntington's Disease (HD) | necroptosis | FOS | Fos proto-oncogene, AP-1 transcription factor subunit | 0.05 | -0.04 | -0.4 | 0.93 | 1.0 | 2.96 | Detail |
261 | Huntington's Disease (HD) | necroptosis | TNFRSF1A | TNF receptor superfamily member 1A | 0.09 | 0.03 | -1.48 | 0.93 | 1.0 | 2.96 | Detail |
262 | Huntington's Disease (HD) | necroptosis | MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.05 | -0.03 | -0.7 | 0.93 | 1.0 | 2.96 | Detail |
263 | Huntington's Disease (HD) | necroptosis | STAT6 | signal transducer and activator of transcription 6 | -0.01 | -0.04 | 2.44 | 0.93 | 1.0 | 2.96 | Detail |
264 | Huntington's Disease (HD) | necroptosis | NLRP3 | NLR family pyrin domain containing 3 | 0.02 | -0.04 | 0.64 | 0.93 | 1.0 | 2.96 | Detail |
265 | Huntington's Disease (HD) | necroptosis | ATF2 | activating transcription factor 2 | -0.06 | -0.08 | 0.28 | 0.94 | 1.0 | 2.63 | Detail |
266 | Huntington's Disease (HD) | necroptosis | TNFAIP3 | TNF alpha induced protein 3 | -0.14 | 0.07 | -1.01 | 0.94 | 1.0 | 2.63 | Detail |
267 | Huntington's Disease (HD) | necroptosis | NR0B2 | nuclear receptor subfamily 0 group B member 2 | 0.13 | 0.1 | -0.36 | 0.94 | 1.0 | 2.63 | Detail |
268 | Huntington's Disease (HD) | necroptosis | CASP7 | caspase 7 | -0.08 | -0.01 | -3.51 | 0.94 | 1.0 | 2.63 | Detail |
269 | Huntington's Disease (HD) | necroptosis | RASA1 | RAS p21 protein activator 1 | -0.03 | -0.09 | 1.59 | 0.95 | 1.0 | 2.3 | Detail |
270 | Huntington's Disease (HD) | necroptosis | PRKCH | protein kinase C eta | 0.07 | 0.08 | 0.15 | 0.95 | 1.0 | 2.3 | Detail |
271 | Huntington's Disease (HD) | necroptosis | NFKBIE | NFKB inhibitor epsilon | 0.03 | 0.01 | -1.93 | 0.96 | 1.0 | 1.97 | Detail |
272 | Huntington's Disease (HD) | necroptosis | TRPM7 | transient receptor potential cation channel subfamily M member 7 | -0.01 | 0.03 | 2.45 | 0.96 | 1.0 | 1.97 | Detail |
273 | Huntington's Disease (HD) | necroptosis | MAPK6 | mitogen-activated protein kinase 6 | -0.06 | -0.0 | -3.68 | 0.96 | 1.0 | 1.97 | Detail |
274 | Huntington's Disease (HD) | necroptosis | ALG2 | ALG2 alpha-1,3/1,6-mannosyltransferase | -0.07 | 0.01 | -2.68 | 0.96 | 1.0 | 1.97 | Detail |
275 | Huntington's Disease (HD) | necroptosis | BFAR | bifunctional apoptosis regulator | 0.02 | 0.06 | 1.58 | 0.96 | 1.0 | 1.97 | Detail |
276 | Huntington's Disease (HD) | necroptosis | NRK | Nik related kinase | 0.07 | -0.06 | -0.32 | 0.96 | 1.0 | 1.64 | Detail |
277 | Huntington's Disease (HD) | necroptosis | TNFRSF1B | TNF receptor superfamily member 1B | -0.07 | -0.02 | -2.05 | 0.97 | 1.0 | 1.32 | Detail |
278 | Huntington's Disease (HD) | necroptosis | IFNG | interferon gamma | -0.0 | 0.08 | 4.47 | 0.97 | 1.0 | 1.32 | Detail |
279 | Huntington's Disease (HD) | necroptosis | VDAC3 | voltage dependent anion channel 3 | -0.11 | -0.02 | -2.14 | 0.97 | 1.0 | 1.32 | Detail |
280 | Huntington's Disease (HD) | necroptosis | GRB2 | growth factor receptor bound protein 2 | -0.07 | -0.05 | -0.38 | 0.98 | 1.0 | 0.99 | Detail |
281 | Huntington's Disease (HD) | necroptosis | RAPGEF2 | Rap guanine nucleotide exchange factor 2 | -0.07 | -0.05 | -0.42 | 0.98 | 1.0 | 0.99 | Detail |
282 | Huntington's Disease (HD) | necroptosis | NFKB1 | nuclear factor kappa B subunit 1 | 0.04 | 0.11 | 1.51 | 0.99 | 1.0 | 0.66 | Detail |
283 | Huntington's Disease (HD) | necroptosis | NFAT5 | nuclear factor of activated T cells 5 | 0.0 | 0.06 | 3.62 | 0.99 | 1.0 | 0.66 | Detail |
284 | Huntington's Disease (HD) | necroptosis | BAX | BCL2 associated X, apoptosis regulator | 0.06 | 0.03 | -1.09 | 1.0 | 1.0 | 0.33 | Detail |
285 | Huntington's Disease (HD) | necroptosis | LMNB1 | lamin B1 | -0.03 | -0.0 | -3.36 | 1.0 | 1.0 | 0.33 | Detail |
286 | Huntington's Disease (HD) | necroptosis | NFKBIL1 | NFKB inhibitor like 1 | 0.02 | 0.0 | -6.48 | 1.0 | 1.0 | 0.33 | Detail |
287 | Huntington's Disease (HD) | necroptosis | ACOD1 | aconitate decarboxylase 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
288 | Huntington's Disease (HD) | necroptosis | TNFRSF6B | TNF receptor superfamily member 6b | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
289 | Huntington's Disease (HD) | necroptosis | ACTG1 | actin gamma 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
290 | Huntington's Disease (HD) | necroptosis | CDK11B | cyclin dependent kinase 11B | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
291 | Huntington's Disease (HD) | necroptosis | PFN1 | profilin 1 | -0.02 | -0.12 | 2.34 | 1.0 | 1.0 | 0.0 | Detail |
292 | Huntington's Disease (HD) | necroptosis | RACK1 | receptor for activated C kinase 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
293 | Huntington's Disease (HD) | necroptosis | TNFSF12 | TNF superfamily member 12 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
294 | Huntington's Disease (HD) | necroptosis | MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
295 | Huntington's Disease (HD) | necroptosis | CDK11A | cyclin dependent kinase 11A | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
296 | Huntington's Disease (HD) | necroptosis | BORCS8-MEF2B | BORCS8-MEF2B readthrough | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
297 | Huntington's Disease (HD) | necroptosis | PYG | unknown | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
298 | Huntington's Disease (HD) | necroptosis | GLNA | unknown | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
299 | Huntington's Disease (HD) | necroptosis | HSP90A | unknown | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
300 | Huntington's Disease (HD) | necroptosis | TNFSF6 | Fas ligand | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
301 | Huntington's Disease (HD) | necroptosis | TNFRSF6 | Fas cell surface death receptor | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
302 | Huntington's Disease (HD) | necroptosis | JNK | mitogen-activated protein kinase 8 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
303 | Huntington's Disease (HD) | necroptosis | CAMK2 | calcium/calmodulin dependent protein kinase II beta | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
304 | Huntington's Disease (HD) | necroptosis | TIRP | TIR domain containing adaptor molecule 2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
305 | Huntington's Disease (HD) | necroptosis | IFNA | interferon alpha 2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
306 | Huntington's Disease (HD) | necroptosis | IFNB | interferon beta 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
307 | Huntington's Disease (HD) | necroptosis | TRIF | TIR domain containing adaptor molecule 1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
308 | Huntington's Disease (HD) | necroptosis | SLC25A4S | unknown | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
309 | Huntington's Disease (HD) | necroptosis | H2A | unknown | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
310 | Huntington's Disease (HD) | necroptosis | VPS24 | charged multivesicular body protein 3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
311 | Huntington's Disease (HD) | necroptosis | CHMP4A | charged multivesicular body protein 4A | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
312 | Huntington's Disease (HD) | necroptosis | VPS4 | vacuolar protein sorting 4 homolog A | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
313 | Huntington's Disease (HD) | necroptosis | CHMP1 | charged multivesicular body protein 1A | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
314 | Huntington's Disease (HD) | necroptosis | PLA2G4 | phospholipase A2 group IVA | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
315 | Huntington's Disease (HD) | necroptosis | NOX2 | cytochrome b-245 beta chain | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | Detail |
Ensemble learning visualization:
Ensemble learning for Huntington's Disease (HD) based on specific necroptosis gene regulaors.
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